Instructions for Use ® Follow this guide to apply NEUPRO (rotigotine transdermal system). Read the Patient Information and Instructions for Use inside the NEUPRO box for complete instructions on the right way to use NEUPRO. When to Apply NEUPRO NEUPRO should be applied right away after • removing it from the protective pouch. Do not damage or cut your NEUPRO patch into smaller pieces Choose the time of day or night that works • best for you to apply your NEUPRO patch. Apply it at the same time each day Wear your NEUPRO patch for 24 hours. • After 24 hours, remove your NEUPRO patch and apply a new one right away to a different area of skin