Why NEUPRO May Be Right for You ® NEUPRO (rotigotine transdermal system) is a prescription medicine used to treat moderate-to-severe primary Restless Legs Syndrome. It’s a patch that delivers the dopamine agonist rotigotine through the skin. With NEUPRO, your RLS symptoms are treated with one patch, once a day. In a 6-month clinical trial, patients with moderate-to-severe primary RLS taking NEUPRO saw improvement in RLS symptoms, as measured by a combined score based on the following 10 items: 1. RLS discomfort in arms and legs 2. Need to move around because of RLS symptoms 3. Relief of RLS discomfort from moving around 4. Sleep disturbance due to RLS symptoms 5. Tiredness or sleepiness during the day due to RLS symptoms 6. Severity of RLS as a whole 7. Frequency of RLS symptoms 8. Severity of RLS symptoms 9. Impact of RLS symptoms on daily activities 10 . Severity of mood disturbance due to RLS symptoms These are legs. They let me walk to the mailbox. I wish they would let me fly to visit family.