• Avoid applying your NEUPRO patch on skin folds. • Do not apply your NEUPRO patch to skin that is red, irritated, or injured. • Avoid applying creams, lotions, ointments, oils, and powders to the skin area where your NEUPRO patch will be placed. How to apply NEUPRO: Step 1. Grasp the two sides of the pouch and pull apart. See Figures C and D. Figure C Figure D Step 2. Remove your NEUPRO patch from the pouch. See Figure E. Figure E Step 3. Hold your NEUPRO patch with both hands, with the protective liner on top. See Figure F. Figure F