Figure A • NEUPRO should be applied right away after removing it from the protective pouch. Do not damage or cut your NEUPRO patch into smaller pieces. • Choose the time of day or night that works best for you to apply your NEUPRO patch. Apply your NEUPRO patch at the same time each day. • Wear your NEUPRO patch for 24 hours. • After 24 hours, remove your NEUPRO patch and apply a new one right away to a different area of your skin. Where to apply NEUPRO: • Choose an area of clean, dry, and healthy skin on the stomach, thigh, hip, side of the body between the ribs and the pelvis (flank), shoulder, or upper arm. See Figure B. Figure B • Apply your NEUPRO patch to a different place on your skin each day, for example, from the right side to the left side and from the upper body to the lower body. Your NEUPRO patch should not be applied to the same area of your skin more than 1 time every 14 days. Apply NEUPRO to a different area of skin (only one of the shaded areas in Figure B) each day to reduce the chance of getting skin irritation. • If you need to apply your NEUPRO patch to a hairy area, the area should be shaved at least 3 days before applying the patch. • Avoid applying your NEUPRO patch to areas where it could be rubbed by tight clothing or under a waistband.