What you should know about NEUPRO®
Interactive Guide | A welcome guide for people living with Parkinson’s disease and their caregivers | 16 Pages
You’re determined to fight the It’s symptoms of Parkinson’s disease. with the 24-hour Your partner, the 24-hour ONNEUPRO Patch. NEUPRO Patch, can help. It’s • 24 hours of continuous medication • Once-daily dosing ON • Pr oven to help control Parkinson’s disease Learn more and sign up for the ™ Patch Partnership Program at www.NEUPROPD.com You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. IMPORTANT SAFETY INFORMATION NEP can cause serious side effects including severe allergic reactions to the ingredient sodium metabisulfite, falling asleep during normal activities, hallucinations holding my grandson and other psychosis, increases or decreases in blood pressure and heart rate, fainting, unusual urges, increased weight gain and fluid retention, and uncontrolled, sudden movements or make those movements you already have worse or happen more often in people with Parkinson’s disease, and skin ® site reactions. What you should know about NEUPRO (rotigotine transdermal system). A welcome guide for people living with Parkinson’s disease and their caregivers. Look inside to see how you may be able to get ® NEUPRO for as low as $10 Please see the Important Safety Information, NEP is a registered trademark, Product Use Brochure and Prescribing and the Neupro Patient ƒavings Program™ and a month for 12 months.* Patch Partnership Program™ are trademarks, * Information for NEUPRO inside. of the … †roup of …ompanies. Eligibility restrictions, terms, ©ˆ‰Š‹ …, nc., ƒmyrna, †A Œ‰‰Ž‰. and conditions apply. All rights reserved. ƒP‘NP‘‰‹Š‹‘‰‰‰Œ’www.NEUPROPD.com or NEP.ormation f nf escribinge and Prochuroduct se rosed Prease see the enclPl INSIE seregivaror patients and ces fc esour• togisolour neuralk with yo tw te on ho Advic• o gett omshipP.cartnerchPat.P isit
What does It’s ON mean to me? morning walks It’s The NEUPRO Patch. Your once-daily partner to ON help treat Parkinson’s disease. WELCOME to NEUPRO. It’s ON. As someone facing the challenges of Parkinson’s disease (PD), you’re determined to fight the symptoms that interfere with your daily activities as much as you can, for as long as you can. n fact, you may e determined like you’ve never een efore. And now that your doctor has chosen P ® (rotigotine transdermal system), It’s ON. Please see the Important Safety Information and enclosed Product Use Brochure and Prescribing Information for NEUPRO at the back of this brochure.
It’s ON because the NEUPRO Patch delivers 24 hours of continuous medicine. And NEUPRO helps improve both motor symptoms and activities of daily living. n clinical trials earlystage P patients taing NEUPRO sa improvement in their Parinson’s symptoms measured by a combination of motor function and activities of daily living. otor function can include tremors stiffness sloness and problems • ith balance. Activities of daily living can include eating dressing and aling. • n clinical studies patients ith advancedstage P ho added NEUPRO to their e€isting medication had almost 2 hours less “off” time—and nearly 2.… hours more “on” time—than patients taing a placebo. †he most common side effects of NEUPRO for P are nausea vomiting sleepiness application site reactions di‡‡iness loss of appetite difficulty falling asleep and staying asleep increased seating vision problems leg selling and uncontrolled sudden movements of arms or legs. ‰ust as you’re determined to face the challenges before you no you have a oncedaily partner to help you manage your symptoms. †hat’s hy It’s ON ith the NEUPRO Patch. n addition there is support available through the Patch Partnership ™ Š Program and you may be able to get savings on your NEUPRO prescription. Š Eligibility restrictions terms and conditions apply. IMPORTANT SAFETY INFORMATION NEUPRO contains a sulfite called sodium metabisulfite. ‹ulfites can cause severe allergic reactions that are life threatening to some people ho are sensitive to sulfites. People ith asthma are more sensitive to sulfites. Remove the patch right aay and call your doctor if you have selling of the lips or tongue chest pain or trouble breathing or salloing. NEUPRO may mae you fall asleep suddenly or ithout arning hile doing normal activities such as driving hich may result in accidents. †ell your doctor right aay if this happens. rining alcohol or taing other medicines that cause drosiness may increase your chances of becoming sleepy hile using NEUPRO. o not drive use ha‡ardous machinery or do other dangerous activities until you no ho NEUPRO affects you.
What does It’s ON mean to me? carrot cake from scratch It’s WHAT is NEUPRO? ON ® NEUPRO Žrotigotine transdermal system‘ is a prescription medicine used to treat Parinson’s disease. NEUPRO is effective in helping to improve movement and activities of daily living in people ith P. NEUPRO is a patch that delivers the dopamine agonist rotigotine through the sin directly into the bloodstream. t releases the medicine 24 hours a day providing stable continuous delivery of medication. WHY NEUPRO may be right for you. NEUPRO may be the first medication your doctor has prescribed for you. Or your doctor may be maing a change because you’ve reached a point here your symptom control isn’t hat it used to be. Or you may feel your medication isn’t helping enough. †his is hen an honest conversation ith your doctor becomes so important to decide if the NEUPRO Patch is right for you. Please see the Important Safet Information an enclose Proct se rochre an Prescriing Information for NEPRO at the ac of this rochre
With NEUPRO, It’s ON in so many ways, because: • Earl€stage P‚ patients ta ing NEPRO saƒ significant impro…ement in Par inson’s smptoms throgh a comine measre of† — Motor fnctions‡ sch as tremors‡ stiffness‡ sloƒness‡ an prolems ƒith alance‡ an — Acti…ities of ail li…ing‡ incling eating‡ ressing‡ an ƒal ing • A…ance€stage P‚ patients ta ing NEPRO in aition to their eˆisting meication ha almost ‰ hors less “off” time—an nearl ‰Ž hors more “on” time—than patients ta ing a placeo — More than tƒice as man P‚ patients ta ing NEPRO ƒo e p “on” efore ta ing morning meication‡ compare to those ta ing placeo • NEPRO is a once a a patch that pro…ies meicine for ‰‘ hors ‚o not se NEPRO if o are allergic to rotigotine or an of the other ingreients in the patch IMPORTANT SAFETY INFORMATION NEUPRO can cause or orsen psychotic symptoms including hallucinations Žseeing or hearing things that are not real‘ confusion e€cessive suspicion aggressive behavior agitation delusional beliefs Žbelieving things that are not real‘ and disorgani‡ed thining. †he chances of having hallucinations or these other psychoticlie changes are higher in people ith Parinson’s disease ho are elderly taing NEUPRO or taing higher doses of NEUPRO. f you have any of these problems tal to your doctor. NEUPRO can cause decreases in blood pressure especially hen you start or increase your dose. ncreases in blood pressure and heart rate fainting eight gain and fluid retention also can occur. f you faint or feel di‡‡y nauseated or seaty hen you stand up from sitting or lying don or have an unusually fast increase in eight selling or fluid retention especially in the anles or legs tell your doctor.
What does It’s ON mean to me? expressing myself It’s ON Please see the Important Safet Information an enclose Proct se rochre an Prescriing Information for NEPRO at the ac of this rochre
WHY a patch may be right for you. ® • NEUPRO Žrotigotine transdermal system‘ provides stable continuous delivery 24 hours a day so you get a consistent level of medication throughout the day. • †he NEUPRO Patch offers oncedaily dosing. ‹imply choose the time of day that ors best for you and apply the patch at the same time each day. • †he medication in the NEUPRO Patch does not go through your digestive system. • ”ood on’t interfere ith ho it ors • No pills to sallo • No need to schedule NEUPRO around meals • †he medication in NEUPRO ill not be affected by the digestive tract NEUPRO can cause nausea vomiting indigestion or upset stomach hich may occur more fre•uently hen you first start using the patch. ‹in reactions may occur at the site here you apply NEUPRO. †ell your doctor if you get a rash redness selling or itching that ill not go aay. IMPORTANT SAFETY INFORMATION ‹ome patients using NEUPRO get urges to behave in a ay that is unusual expressing myself for them such as unusual urges to gamble strong urges to spend money binge eating or increased se€ual urges and behaviors. f you or your family notices you are developing any unusual behaviors tal to your doctor. NEUPRO may cause uncontrolled sudden movements or mae such movements you already have orse or more fre•uent if you have Parinson’s disease hich may mean that your antiParinson’s medicine needs to be changed.
What does It’s ON mean to me? enjoying a cup of tea It’s SAVINGS, tools, and support. ON ™ It’s ON with the Patch Partnership Program . –e no managing Parinson’s involves more than —ust managing ™ symptoms. Our Patch Partnership Program is designed to be your helpful guide for financial assistance understanding Parinson’s and getting a head start on conversations ith your neurologist ith suggestions for •uestions and topics to discuss. ’isit ƒƒƒNEPROSa…ingsP‚com to find out ho you may be able to get™ ® • NEPRO ”rotigotine transermal sstem• for as loƒ as –—˜ a month ™™ for —‰ months ƒith the NEPRO Patient Sa…ings Program If o’re eligile‡ o can oƒnloa or car an start sa…ing on or neˆt NEPRO prescription Š Eligibility restrictions terms and conditions apply. Please see the Important Safet Information an enclose Proct se rochre an Prescriing Information for NEPRO at the ac of this rochre
’isit ƒƒƒPatchPartnershipP‚com to get™ • A…ice on hoƒ to tal ƒith or nerologist • Resorces for patients an caregi…ers CARING for someone with Parkinson’s? There are resources for you, too. –hen you care for someone ith Parinson’s you ant to do everything you can to help mae them feel better. †hat’s hy e thin you’ll appreciate the NEUPRO Patch for the symptom control it can help provide as ell as the oncedaily application. –e also hope the financial educational and support ™ services that are available ith our Patch Partnership Program can help you and the one you’re caring for in all inds of ays. n short e’ll or hard to be the best partner e can so you can eep being the best partner you can. f you have any more •uestions about the NEUPRO Patch these resources may help™ ON • ’isit ƒƒƒNEPROP‚com† • For information tailore to caregi…ers • For a emonstration …ieo an instrctions on appling the NEPRO Patch ™ • To sign p for the Patch Partnership Program an the ™ NEPRO Patient Sa…ings Program • šall the toll€free help line at —€›‘‘€Žœœ€‰‰žŸ if o ha…e ¡estions aot hoƒ to appl the NEPRO Patch IMPORTANT SAFETY INFORMATION ‹in reactions may occur at the site here you apply NEUPRO. †ell your doctor if you get a rash redness selling or itching that ill not go aay. ‹ome people ith Parinson’s disease may have an increased chance of getting a sin cancer called melanoma. šou should have your sin checed by a doctor regularly.
What does It’s ON mean to me? making dinner together It’s ON HOW to apply the NEUPRO Patch. It is important to appl the patch correctl Please see the enclose NEPRO Proct se rochre for complete step€€step instrctions e sre to as or octor or pharmacist aot anthing o o not nerstan For more information FPO …isit ƒƒƒApplThePatchP‚com an ƒatch the “¢oƒ to Appl the Patch” …ieo Please see the Important Safet Information an enclose Proct se rochre an Prescriing Information for NEPRO at the ac of this rochre
FAQs. Frequently asked questions about ® NEUPRO (rotigotine transdermal system). 1. Can I get my NEUPRO Patch wet? šes. šou can bathe shoer or sim hile earing the NEUPRO Patch. ›oever ater may loosen your patch. Avoid hot baths as the heat may cause too much medicine to pass through the sin. 2. What if my NEUPRO Patch falls off? f your patch falls off put on a fresh patch until the time you usually change your patch. †hen put a ne patch on a different part of your sin at your regular scheduled time. f the edges of the patch lift you may tape them don ith bandaging tape. 3. What if I forget to t on my NEUPRO Patch? f you miss a dose or forget to change your NEUPRO patch apply a ne NEUPRO patch as soon as you remember. Replace the NEUPRO patch at your normal time the ne€t day. . ow long oes it tae for the NEUPRO Patch to start woring? šour doctor should start you on a lo dose of NEUPRO. šour doctor may change the dose eely until you are taing the right amount of medicine to control your symptoms. t may tae several ees before you reach the dose that controls your symptoms best. IMPORTANT SAFETY INFORMATION Avoid e€posing the NEUPRO patch you are earing to heating pads electric blanets heat lamps saunas hot tubs heated ater beds and direct sunlight. †oo much medicine could be absorbed into your body. Also do not ear NEUPRO during medical procedures called magnetic resonance imaging ŽR‘ or cardioversion because this could cause sin burns.
Frequently asked questions, continued. . What shol I aoi while taing NEUPRO? o not drive operate machinery or do other dangerous activities until you no ho NEUPRO affects you. Avoid e€posing the NEUPRO Patch you are earing to heating pads electric blanets heat lamps saunas hot tubs heated ater beds and direct sunlight. †oo much medicine could be absorbed into your body. o not use NEUPRO during certain medical procedures called magnetic resonance imaging ŽR‘ or cardioversion. Using NEUPRO during these procedures could cause a burn to the site here you applied your NEUPRO Patch. €. ‚o I hae to aly my NEUPRO Patch aron mealtime? No. Apply your patch hen it’s convenient for you and apply it at the same time each day. œecause NEUPRO is delivered through the sin food should not affect the medication. ƒ. Why o I nee to hol the NEUPRO Patch on for at least 3„ secons? Press your NEUPRO Patch firmly ith the palm of your hand for žŸ seconds to mae sure there is good contact ith your sin especially around the edges. †he armth of your hand helps the adhesive on the patch stic to your sin. ae sure that your NEUPRO Patch is flat against your sin. †here should be no bumps or folds in your NEUPRO Patch. …. ow can I reent sin irritation or other sin†relate sie effects? šou need to change the location of the NEUPRO Patch on a daily basis and should not use the same location for ¡4 days. ¢hanging the location ill reduce the chance of getting sin irritation. šou may see mild redness lie hen you remove an adhesive bandage hich is normal. Of course alays chec ith your doctor if you have any concerns. Patients should report application site reactions that do not go aay after a fe days that get orse or that spread outside the patch site. f there is a sin rash or irritation from the patch direct sunlight on the area should be avoided until the sin heals. E€posure could lead to changes in sin color. †he NEUPRO Patch Placement †racer can help you rotate your application site every day. ’isit ƒƒƒNEPROP‚com to donload the †racer no. Please see the Important Safet Information an enclose Proct se rochre an Prescriing Information for NEPRO at the ac of this rochre
Patch Images Note to designers: When using more than one group of patches in a layout, please be sure to scale the images uniformly. All files are CMYK format, please convert to rgb for web. ‡. ow o I safely sto sing the NEUPRO Patch? o not stop or change your treatment ith NEUPRO ithout taling to your doctor. 1„. What oes the NEUPRO Patch loo lie? ® NEUPRO Žrotigotine transdermal system‘ is a small thin fleshcolored patch that comes in 4 si‡es based on dosage 2 mg 4 mg £ mg and ¤ mg. Actual patch. 11. ow can I sae on NEUPRO? Not shon actual si‡e. ™Š †he NEUPRO Patient ‹avings Program is here to help. ’isit ƒƒƒNEPROSa…ingsP‚com to see if you are eligible to donload your savings card today. Š Eligibility restrictions terms and conditions apply. šall the toll€free help line at —€›‘‘€Žœœ€‰‰žŸ if you have additional •uestions about the NEUPRO Patch. IMPORTANT SAFETY INFORMATION †ell your doctor if you have breathing problems a sleep disorder mental problems high or lo blood pressure or heart problems¥ are pregnant or plan to become pregnant¥ or are breastfeeding or plan to breastfeed. NEUPRO may not be right for you. †he most common side effects in people taing NEUPRO for Parinson’s disease are nausea vomiting sleepiness application site reactions di‡‡iness loss of appetite difficulty falling asleep and staying asleep increased seating vision problems leg selling and uncontrolled sudden movements of the arms or legs. Notes It’s ON
IˆPOR‰ŠN‰ ‹ŠŒE‰Ž INŒORˆŠ‰ION NEUPRO contains a sulfite called sodium metabisulfite. ‹ulfites can cause severe allergic reactions that are life threatening to some people ho are sensitive to sulfites. People ith asthma are more sensitive to sulfites. Remove the patch right aay and call your doctor if you have selling of the lips or tongue chest pain or trouble breathing or salloing. NEUPRO may mae you fall asleep suddenly or ithout arning hile doing normal activities such as driving hich may result in accidents. †ell your doctor right aay if this happens. rining alcohol or taing other medicines that cause drosiness may increase your chances of becoming sleepy hile using NEUPRO. o not drive use ha‡ardous machinery or do other dangerous activities until you no ho NEUPRO affects you. NEUPRO can cause or orsen psychotic symptoms including hallucinations Žseeing or hearing things that are not real‘ confusion e€cessive suspicion aggressive behavior agitation delusional beliefs Žbelieving things that are not real‘ and disorgani‡ed thining. †he chances of having hallucinations or these other psychoticlie changes are higher in people ith Parinson’s disease ho are elderly taing NEUPRO or taing higher doses of NEUPRO. f you have any of these problems tal to your doctor. NEUPRO can cause decreases in blood pressure especially hen you start or increase your dose. ncreases in blood pressure and heart rate fainting eight gain and fluid retention also can occur. f you faint or feel di‡‡y nauseated or seaty hen you stand up from sitting or lying don or have an unusually fast increase in eight selling or fluid retention especially in the anles or legs tell your doctor. ‹ome patients using NEUPRO get urges to behave in a ay that is unusual for them such as unusual urges to gamble strong urges to spend money binge eating or increased se€ual urges and behaviors. f you or your family notices you are developing any unusual behaviors tal to your doctor. NEUPRO may cause uncontrolled sudden movements or mae such movements you already have orse or more fre•uent if you have Parinson’s disease hich may mean that your antiParinson’s medicine needs to be changed. ‹in reactions may occur at the site here you apply NEUPRO. †ell your doctor if you get a rash redness selling or itching that ill not go aay. ‹ome people ith Parinson’s disease may have an increased chance of getting a sin cancer called melanoma. šou should have your sin checed by a doctor regularly. Avoid e€posing the NEUPRO patch you are earing to heating pads electric blanets heat lamps saunas hot tubs heated ater beds and direct sunlight. †oo much medicine could be absorbed into your body. Also do not ear NEUPRO during medical procedures called magnetic resonance imaging ŽR‘ or cardioversion because this could cause sin burns. †ell your doctor if you have breathing problems a sleep disorder mental problems high or lo blood pressure or heart problems¥ are pregnant or plan to become pregnant¥ or are breastfeeding or plan to breastfeed. NEUPRO may not be right for you. †he most common side effects in people taing NEUPRO for Parinson’s disease are nausea vomiting sleepiness application site reactions di‡‡iness loss of appetite difficulty falling asleep and staying asleep increased seating vision problems leg selling and uncontrolled sudden movements of the arms or legs.
isit .PatchPartnershipP.com to get • Advice on how to talk with your neurologist • esources for patients and caregivers INSIE Please see the enclosed Product se rochure and Prescribing nformation for NEP. .com.NEUPROPDwww ed. ƒP‘NP‘‰‹Š‹‘‰‰‰Œ’eservAll rights r .yonditions appland cA Œ‰‰Ž‰. ©ˆ‰Š‹ …, nc., ƒmyrna, † inside. NEUPRO rfo ormationInf erms,trictions, tesEligibility r* oup of …ompanies. of the … †r a month for 12 months. ademarks,e tram™ arogrship Prartnerch PatP escribingPr and eochurBr Use oductPr * am™ andogr atient ƒavings Pro Pand the Neupr ormation,Inf etySaf antImport the see easePl w as $10 for as loNEUPRO ademark,ed trertegis is a r®NEP etou may be able to gy wLook inside to see hos.eregivars disease and their carkinson’P e living withor peoplome guide fcelA w ansdermal system).otine trotig(r ®w about NEUPROou should knoWhat y eactions.e rsit s disease, and skinarkinson’e with Pin peopl en e oft se or happen morore weady havalr ou ements yv e those mo ements or makvmo ed, suddenollontr ention, and uncetfluid r eight gain andeased wges, incrunusual ur ainting,e, fat e and heart rsuresood prin bl ndsonay grg mnidhol eases eases or decrchosis, incr and other psy hallucinationsactivities, normal during eep asl allinge, f abisulfit edient sodium metingr o the eactions tgic rere allerv including se ects ause serious side effan cNEP c TION ORMA ANT SAFETY INFIMPORT A-1088. or call 1-800-FD atch v/medwo .fda.g wwwisit A. VFD escription drugs to thefects of prside ef e eport negatived to rage encourou arY .com .NEUPROPDwww at™ am ogr ship Prartner atch PP e and sign up for then mor Lear s disease arkinson’P ol en to help contrvo Pr • ON • Once-daily dosing s of continuous medication• 24 hour sIt’ can help. the 24-hour,atch, Pour partnerYNEUPRO atch. with the 24-hourNEUPRO PON .s diseasearkinson’symptoms of P s It’ e determined to fight therou’Y
You’re determined to fight the It’s symptoms of Parkinson’s disease. with the 24-hour Your partner, the 24-hour ONNEUPRO Patch. NEUPRO Patch, can help. It’s • 24 hours of continuous medication • Once-daily dosing ON • Pr oven to help control Parkinson’s disease Learn more and sign up for the ™ Patch Partnership Program at www.NEUPROPD.com You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. IMPORTANT SAFETY INFORMATION NEP can cause serious side effects including severe allergic reactions to the ingredient sodium metabisulfite, falling asleep during normal activities, hallucinations holding my grandson and other psychosis, increases or decreases in blood pressure and heart rate, fainting, unusual urges, increased weight gain and fluid retention, and uncontrolled, sudden movements or make those movements you already have worse or happen more often in people with Parkinson’s disease, and skin ® site reactions. What you should know about NEUPRO (rotigotine transdermal system). A welcome guide for people living with Parkinson’s disease and their caregivers. Look inside to see how you may be able to get ® NEUPRO for as low as $10 Please see the Important Safety Information, NEP is a registered trademark, Product Use Brochure and Prescribing and the Neupro Patient ƒavings Program™ and a month for 12 months.* Patch Partnership Program™ are trademarks, * Information for NEUPRO inside. of the … †roup of …ompanies. Eligibility restrictions, terms, ©ˆ‰Š‹ …, nc., ƒmyrna, †A Œ‰‰Ž‰. and conditions apply. All rights reserved. ƒP‘NP‘‰‹Š‹‘‰‰‰Œ’ www.NEUPROPD.com or NEP. ormation f nf escribing e and Pr ochur oduct se r osed Pr ease see the enclPl INSIE s er egiv ar or patients and ces fc esour• t ogis ol our neur alk with yo t w t e on ho Advic• o gett om shipP.c artner chP at .P isit
